Botulinum toxin is a very potent natural toxin. It is produced by the bacterium Clostridum botulinum, and its action consists in inhibiting the release of acetylcholine, i.e. a neurotransmitter that is responsible for the transmission of impulses on the nerve-muscle line. Thus, properly administered botulinum toxin prevents the formation and deepening of wrinkles. There is a shutdown or limitation of the work of selected facial muscles, which deepened wrinkles due to excessive wrinkling of the skin.

At Angel Clinic, treatments with botulinum toxin are performed in anti-aging therapies, in the treatment of hyperhidrosis and in the treatment of migraine.

In treatments aimed at eliminating mimic wrinkles, very low concentrations of botulinum toxin are administered, which makes the treatment completely safe and the given preparation does not affect other elements of the nervous system – it works only at the injection site. It is recommended that botulinum toxin treatments be repeated about every 6 months, or after a longer period – after the return of full facial expressions, which causes the reappearance of unwanted furrows and lines. In the case of migraine treatment, shorter intervals are recommended – an average of 6-12 weeks, determined individually with the doctor.


  • forehead wrinkles
  • wrinkles between the eyebrows (lion’s wrinkle)
  • wrinkles around the eyes (crow’s feet)
  • nose wrinkles (rabbit lines)
  • wrinkles around the mouth (marionette lines, smoker’s lines)
  • excessive sweating
  • migraine
  • bruxism


  • neuromuscular conduction disorders (myasthenia gravis, Lambert Eaton syndrome)
  • hypersensitivity to the ingredients of Botox and Azzalure (human albumin)
  • use of the following medications or for up to 1 week of discontinuation: aminoglycosides (streptomycin, gentamicin, amikacin, kanamycin, etc.), aminoquinolones (chloroquine, hydroxychloroquine), D-penicillamine (Cuprenil), cyclosporin, tubocurarine, pancuronium, galamine, succinylcholine , lincomycin, tetracycline, polymyxin
  • local skin infections
  • pregnancy, lactation period


At Angel Clinic, we take care of every detail that will make you feel like an angel in our offices. We follow trends on an ongoing basis.